| 4+ | Desperate Ritual | MTGChampions_163 |
| 4+ | Desperate Ritual | MTGModernMasters_110 |
| 1 | Desperate Ritual | MTGUltimateMasters_127 |
| 4+ | Desperate Sentry | MTGEldritch Moon_021 |
| 4+ | Desperate Stand | MTGJourneyNyx_147 |
| 4+ | Despise | MTGNewPhyrexia_056 |
| 4+ | Despise | MTGKhansofTarkir_069 |
| 4+ | Despoil | MTGProphecy_062 |
| 1 | Despoiler of Souls | MTGMagicOrigins_093 |
| 4+ | Despondency | MTGUrzaSaga_129 |
| 4+ | Despotic Scepter | MTGICE_316 |
| 4+ | Destined // Lead | MTGAmonkhet_217 |
| 1 | Destiny Spinner | MTGTherosBeyondDeath_168 |
| 4+ | Destroy the Evidence | MTGReturntoRavnica_064 |
| 1 | Destroy the Evidence (FOIL) | MTGReturntoRavnica_064F |
| 4+ | Destructive Digger | MTGCore Set 2020_134 |
| 1 | Destructive Digger (FOIL) | MTGCore Set 2020_134F |
| 4+ | Destructive Flow | MTGPlaneshift_102 |
| 4+ | Destructive Force | MTGMagic2011_133 |
| 1 | Destructive Force FOIL | MTGMagic2011_133F |
| 4+ | Destructive Revelry | MTGDDHeroes_066 |
| 4+ | Destructive Revelry | MTGTheros_192 |
| 1 | Destructive Revelry (FOIL) | MTGTheros_192F |
| 3 | Destructive Tampering | MTGAether Revolt_078 |
| 4+ | Destructive Tampering | MTGCore Set 2021_141 |
| 4+ | Destructive Tampering | MTGGameNight2019_038 |
| 1 | Destructive Tampering (FOIL) | MTGCore Set 2021_141F |
| 4+ | Destructive Urge | MTGUrzaSaga_180 |
| 4+ | Destructor Dragon | MTGFateReforged_127 |
| 4+ | Detainment Spell | MTGTimespiral_012 |
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